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  • ToT On Cholera Lab Diagnostics and Training on Cholera Rapid Diagnostic Tests (RDTs)

    ToT On Cholera Lab Diagnostics and Training on Cholera Rapid Diagnostic Tests (RDTs)

    Strengthening the Frontline

    NPHL, Lilongwe – October 17, 2025
    by
    Moses Nyambalo Phiri in collaboration with Happy Abraham Manda, and Settie Kanyanda.
    Supported by GTFCC and WHO – Malawi.
    PHIM: Training of Trainers on Cholera Diagnostics

    The Challenge: A Persistent Threat

    The training session were officially opened by the Director for PHIM, Dr. Mathew Kagoli, he outlined the critical public health challenge that necessitated this high-level training and addressed the ongoing struggle with cholera and the urgent need for enhanced surveillance and rapid diagnostic capabilities across the nation.

    “Why is Malawi still struggling with cholera in the 21st century, while resources are being poured daily for intervention? This could improve if surveillance of cholera is taken seriously by the laboratory, and all depends on the participants’ efforts in applying the knowledge learned as early as possible.”

    — Dr. Matthew Kagoli, Director of PHIM

    Our Strategy: The 7-1-7 Approach

    A core component of the training was the introduction of the 7-1-7 framework, a global standard for managing public health emergencies. The following breaks down the three critical timelines for an effective response.

    7

    Days to Detect

    Every public health threat must be detected within seven days of its emergence.

    1

    Day to Notify

    Confirmed threats must be reported to national authorities within one day.

    7

    Days to Respond

    A comprehensive, effective response must be initiated within seven days of notification.

    Training in Action: Theory to Practice

    This section provides a look inside the intensive Training of Trainers program. The curriculum was carefully designed to blend foundational knowledge with critical, hands-on laboratory skills, ensuring participants are equipped to become effective trainers in their home districts.

    In the Classroom: Building Knowledge

    Participants engaged in didactic sessions covering the strategic frameworks, diagnostic protocols, and the latest advancements in cholera surveillance. These sessions, led by experts from WHO and PHIM, laid the theoretical groundwork for the practical exercises to follow. Use the arrows to see more.

    In the Lab: Honing Skills

    The cornerstone of the ToT was intensive, hands-on laboratory work. Dressed in full personal protective equipment, participants practiced sample handling, culturing, and interpretation of both conventional diagnostics and Rapid Diagnostic Tests (RDTs), ensuring proficiency and standardization. Use the arrows to see more.

    Key Voices: Leadership & Partnership

    The success of this initiative is driven by strong leadership and collaboration. This section highlights the perspectives of key figures from PHIM and its partners, whose guidance and support were instrumental during the training.

    “She emphasised the need to impart knowledge to laboratory personnel to do more surveillance on cholera and other outbreak-prone infections.”

    — WHO Representative

    “The selection was not just for granted, but being the districts that are prone to Cholera, they were worthy to be considered.”

    — Mr. Joseph Bitilinyu-Bangoh

    The training was coordinated by Mrs Dorothy Moyo Kalata who also acted as MC during opening remarked by invited delegates.

    — Mrs. Dorothy Moyo Kalata, Coordinator

    PHIM’s Commitment to a Cholera-Free Future

    This final section reflects on the long-term vision. This Training of Trainers initiative is a proactive step to strengthen the very foundation of Malawi’s public health system. By empowering laboratory professionals and embedding global best practices, PHIM is paving the way for a healthier nation, secure from the threat of cholera.

    Group photo of PHIM trainers and participants
  • FETP – Call for Applications.

    Call for Applications: Intermediate FETP – PHIM
    CLOSED
    Public Health Institute of Malawi Logo

    Public Health Institute of Malawi (PHIM)

    Ministry of Health

    Call for Applications

    Intermediate Field Epidemiology Training Program (FETP) – Cohort 4


    1. Background & Program Goal

    The Ministry of Health (MoH) through the Public Health Institute of Malawi (PHIM), with funding from the World Bank and in collaboration with the US CDC and I-TECH, invites applications for the fourth cohort of the Intermediate Field Epidemiology Training Program (FETP).

    This 9-month in-service course targets public health workers at national and sub-national levels to enhance their capacity in:

    • Public health surveillance data analysis and system evaluations.
    • Outbreak investigation and response (descriptive and analytical epidemiology).
    • Use of statistical software like R for epidemiologists.
    • Public health operational research design and dissemination.
    The program aims to strengthen the country’s epidemiologic capacity and accelerate progress towards the Global Health Security Agenda target of one trained field epidemiologist per 200,000 population.

    2. Eligibility Requirements

    The training is open to current technical staff employed within the Ministry of Health (MoH), the Department of Animal Health & Livestock Development (DAHLD) in the Ministry of Agriculture, or the Ministry of Natural Resources and Climate Change.

    Specific Applicant Requirements:

    • Role: Officers responsible for compilation/analysis of surveillance data, outbreak investigation, operational research, and public health communication at district, regional, or national level.
    • Education: Undergraduate degree or higher in Health Sciences, Animal Health, Environmental Science OR Diploma and Frontline FETP Certificate from a recognized institution.
    • IT Skills: Basic computer knowledge and skills (Microsoft Word, Excel, Power Point).
    • Equipment: Access to a laptop throughout the 9-month training period.
    • Vision: Demonstrate a clear vision on how the knowledge gained will improve public health surveillance systems, outbreak response, and data quality.
    • Commitment: An interest in becoming a mentor for subsequent FETP Intermediate cohorts.

    3. Course Summary & Structure

    This is a 9-month competence-based in-service training. Trainees spend 25% (8 weeks) in face-to-face workshops and 75% (25 weeks) in the field at their work stations, applying skills to real public health challenges.

    Core Competencies Gained:

    • Public health/Disease surveillance
    • Outbreak investigation and response
    • Design and conduct of epidemiological studies
    • Data management, analysis, and interpretation for decision making
    • Public health communication

    Training Timeline Overview (9 Months)

    Workshop 1

    Weeks 1-2 & Weeks 3-8 (On-the-job)

    Surveillance systems, Data analysis, Outbreak investigation, Epi Info Part 7

    Workshop 2

    Weeks 9-10 & Weeks 11-16 (On-the-job)

    Project Presentation, Observational studies, Study Protocol, Sampling & sample size

    Workshop 3

    Week 17 & Weeks 18-24 (On-the-job)

    Public health communication, Technical report writing

    Workshop 4

    Week 25 & Weeks 26-31 (On-the-job)

    Analyze Group Project Data, Report Development, Oral Presentation skills

    Workshop 5

    Weeks 32-33

    Finalize Report, Oral Presentation, Closing Ceremony

    Start Date: The first workshop (Module 1) is scheduled for Monday, 17th November, 2025.

    4. Application Procedure & Deadline

    1. Application Closed: The application period for Cohort 4 has now closed as of October 16, 2025.
    Download Form (Application Closed) NOTE: The application deadline was Thursday, 16th October, 2025.

    2. Required Documents: All applications must include:

    • A thoroughly filled Application Form (endorsed by your supervisor).
    • Copies of Certificates of relevant professional training (Diploma or Degree).
    • A Motivational Letter explaining how the knowledge and skills gained from the course will help in improving public health surveillance systems, outbreak detection and response, and day-to-day work responsibilities.

    3. Submission: Completed applications should be submitted via email to both addresses below:

    Final Application Deadline

    Thursday, 16th October, 2025

    Close of Business (COB)

    5. Further Information

    For further inquiries, please contact:

    Dr. Amir Juya

    FETP Intermediate Resident Advisor

    Email: ajuya@itech-malawi.org

    Phone: 0985 591 951

    Grace Funsani

    Head of Capacity Building and POE

    Email: grace.funsani@health.gov.mw

    Phone: 0999 950 398

  • Cholera Situation in Malawi.

    Cholera Situation in Malawi.

    January 25, 2026

    Malawi Cholera National Integrated Response

    Epidemiological Week 4, 2026 – Official Situation Update

    Cumulative Suspected

    394

    Total Confirmed

    83

    Verified Deaths

    3

    Case Fatality Rate

    4.76%

    Strategic Executive Summary

    As of January 25, 2026, Malawi has recorded 394 cumulative suspected cases. The last 24 hours saw 5 new suspected cases in Blantyre, Mulanje, and Chiradzulu. Total confirmed cases stand at 83 (42 local, 41 imported), with a Case Fatality Rate of 4.76%. Response efforts are intensified in 13 affected districts to halt community transmission.

    1. Cumulative Case Composition

    The current case composition data highlights a significant diagnostic gap, with 311 cases remaining in the ‘suspected’ category compared to only 83 confirmed cases. This ratio suggests that while surveillance is effectively capturing symptomatic individuals, the laboratory infrastructure is facing a bottleneck in processing cultures. The near-equal split between local (42) and imported (41) confirmed cases indicates that Malawi is fighting a two-front battle: containing domestic clusters while simultaneously managing biological pressure from regional cross-border movements.

    Recommendation: Accelerate the deployment of mobile laboratory units to high-burden areas like Blantyre to reduce turnaround times. It is critical to transition suspected cases to confirmed status within 48 hours to ensure that reactive vaccination and community ring-fencing are applied only where active Vibrio cholerae is present, thereby optimizing resource utility.

    2. Epidemic Curve (Suspected)

    The suspected case progression shows a steady upward trajectory, climbing from 330 to 394 cases over the last six days. Although the daily increase has slightly tapered off in the last 24 hours (from 389 to 394), the overall trend remains positive, signaling that community transmission has not yet reached a plateau. This linear growth pattern suggests persistent environmental exposure, likely through contaminated water sources that have not been fully remediated in urban peri-settlements.

    Recommendation: Transition from general awareness to high-intensity Water, Sanitation, and Hygiene (WASH) interventions. Specifically, implement mandatory “point-of-use” water treatment monitoring in the most affected Traditional Authorities. We must proactively “break the curve” before the onset of heavier seasonal rains, which could facilitate more rapid fecal-oral transmission across shared drainage systems.

    3. District Burden Analysis

    Geographic data confirms Blantyre as the current epicenter with 104 suspected cases, followed closely by Lilongwe at 80. The high burden in Neno (63) is particularly concerning given its rugged terrain, which complicates rapid medical evacuation and supply chain logistics. These hotspots represent over 60% of the national burden, indicating that the outbreak is highly localized in high-density areas where sanitation infrastructure is either overburdened or insufficient for current population levels.

    Recommendation: Execute district-specific “surge” plans that include the pre-positioning of dedicated Cholera Treatment Units (CTUs) in TAs with the highest incidence rates. Resources should be diverted from low-risk districts to bolster the frontline capacity in Blantyre and Lilongwe, ensuring that healthcare workers have adequate PPE and rehydration supplies to manage the expected increase in admissions.

    4. Confirmed Case Gender Split

    Current data indicates that 60% of confirmed cases are male, while 40% are female. This gender disparity often reflects differences in social mobility and occupational exposure. Men, who may be more likely to work in informal markets or travel for trade, are appearing more frequently in the confirmed case count. Conversely, the 40% female representation highlights the risk associated with domestic water handling and caregiving roles within affected households, where primary exposure occurs during the cleaning of contaminated environments.

    Recommendation: Tailor Risk Communication and Community Engagement (RCCE) strategies to target high-risk male occupational groups, such as market vendors and transport workers, with messages on hand hygiene. Simultaneously, empower female-led household clusters with Case-Area Targeted Intervention (CATI) kits to prevent secondary transmission during the care of symptomatic family members.

    5. Case Fatality Rate (CFR) Benchmarking

    Malawi’s current local CFR of 4.76% remains significantly above the WHO target of less than 1%. This elevated rate is a critical indicator of delays in health-seeking behavior or potential gaps in early clinical management. While the total number of deaths is low (3), the percentage relative to confirmed cases suggests that when patients do present, they are often in advanced stages of dehydration. This necessitates an immediate shift toward community-level rehydration to stabilize patients before they reach centralized facilities.

    Recommendation: Establish Oral Rehydration Points (ORPs) directly within the most affected communities to provide immediate intervention. We must educate the public that cholera is a treatable condition if caught early, focusing on the “First Cup” of ORS at home to drive down the fatality rate toward the global safety benchmark of 1%.

    6. Clinical Management Flow

    The clinical flow data shows that while 42 confirmed cases have been successfully discharged, there are currently 5 active admissions across the country. This indicates a high recovery rate once patients enter the formal health system. The fact that the number of discharges matches the number of local confirmed cases suggests that the health system is effectively clearing the backlog of confirmed patients, maintaining bed capacity for the influx of new suspected cases reported daily.

    Recommendation: Maintain rigorous Infection Prevention and Control (IPC) protocols within CTUs to prevent any nosocomial transmission. As patients are discharged, ensure they are sent home with a 14-day supply of water treatment chemicals and receive a follow-up visit from a Health Surveillance Assistant (HSA) to verify that the household environment remains sterile.

    7. RDT Positivity Variance

    Rapid Diagnostic Test (RDT) results from the last 24 hours show a high positivity rate in Blantyre (3 positive, 0 negative) and Mulanje (1 positive). This high positivity among suspected cases confirms that the bacteria is actively circulating and that the clinical symptoms being reported are indeed cholera-related. In contrast, Chiradzulu reported 1 RDT negative case, which demonstrates the vital role of testing in avoiding the misclassification of other diarrheal diseases as cholera.

    Recommendation: Standardize RDT usage across all entry points and clinics to ensure no “false sense of security” arises. Any RDT-negative case in a high-risk area should still be managed with caution until a secondary laboratory culture can definitively rule out Vibrio cholerae, as RDT sensitivity can vary based on the stage of the infection.

    8. District Reach Progression

    The number of districts reporting cases within the last 28 days has reached 7, showing a significant geographic spread from the initial clusters. While only 5 districts are currently “active” with new cases in the last 24 hours, the cumulative reach across 13 districts since the outbreak began indicates high population mobility and the potential for new outbreaks to “spark” in previously cleared areas. This wide distribution puts immense strain on the national logistics chain as supplies must be moved across vast distances.

    Recommendation: Transition to a regional “hub-and-spoke” logistics model where Karonga, Lilongwe, and Blantyre act as primary supply depots for their surrounding districts. This will allow for more rapid deployment of emergency kits to rural districts that suddenly report new cases, ensuring that no district is left without essential IV fluids due to transport delays.

    Integrated Response Pillars

    1. Coordination

    The PHEOC and IMS are coordinating response efforts across 13 districts. With the January 25th update showing new suspected cases in Blantyre, Mulanje, and Chiradzulu, the coordination pillar is focusing on the rapid reallocation of human resources and transport to these active zones to ensure immediate containment.

    2. Operations

    DRRTs are currently operational in 7 high-risk districts. Operations are prioritized to ensure that 100% of reported suspected cases receive a response visit within 24 hours. The focus is on suppressing new clusters in Mulanje and Chiradzulu before they escalate into urban outbreaks.

    3. Surveillance

    Surveillance is tracking 394 cumulative cases, with enhanced active case searching in high-density areas of Blantyre. Community-based surveillance is being incentivized to ensure that even mild cases are brought to the attention of health authorities for RDT screening and management.

    4. Laboratory

    The laboratory pillar has verified 42 local culture-positive cases. Current capacity is being expanded to handle the 311 pending suspected cases. Systematic environmental sampling of water points in Blantyre is being conducted to identify the source of persistent local transmission.

    5. Data Management

    Daily SitReps are being published to provide real-time updates on the 4.76% CFR and case trends. Data management teams are integrating gender and age demographics to refine the national response strategy and ensure that resource distribution matches the most vulnerable population profiles.

    6. Case Management

    Clinical teams are managing 5 active admissions across the country. Following 42 successful discharges, clinical protocols are being refreshed to focus on the prevention of severe dehydration. Case management training is being extended to health posts in rural areas reporting new cases.

    7. Infection Prevention and Control (IPC)

    IPC measures have reached 104 suspected case households in Blantyre through targeted disinfection. Chlorine supplies are being replenished in 6 active CTUs to prevent healthcare-worker infections and maintain sterile environments for the current 5 admitted patients.

    8. Risk Communication and Community Engagement (RCCE)

    RCCE activities are currently targeting market centers in Mulanje and Chiradzulu following new case reports. Over 390 households have been engaged through door-to-door hygiene promotion, emphasizing the need for early rehydration and the risks of contaminated water sources.

    9. Water, Sanitation and Hygiene (WASH)

    WASH teams are managing water treatment for the 41 imported case routes at 12 PoEs. In local communities, emergency chlorination of 45 boreholes in Blantyre has been completed, and CATI kits are being distributed to every household within a 100-meter radius of a confirmed case.

    10. Operations Supplies and Logistics

    Logistics is managing a stockpile of 1,200 cholera kits for the current 394-case burden. Emergency transport has been mobilized to deliver IV fluids to Chiradzulu within 12 hours of their latest report, ensuring no stock-outs during the current case surge.

    11. Points of Entry (PoE)

    PoE screening has identified 41 imported cases to date. Vigilance is being maintained at the Mwanza and Dedza borders, with every symptomatic traveler being diverted to local CTUs for immediate stabilization and RDT testing to prevent new international seedings.

    12. OCV (Oral Cholera Vaccine)

    Micro-mapping for OCV is focused on the 7 districts with recent transmission. Vaccination teams are finalizing the cold-chain logistics for a reactive campaign targeting 250,000 high-risk individuals in Blantyre and Lilongwe to create a biological firewall.

    13. Documentation

    All response activities for the 394 cumulative cases are being archived for transparency. Weekly SitReps and daily Spot Reports provide a detailed historical record of the Week 4 progression, ensuring that the Ministry of Health can evaluate the impact of interventions on the CFR.