PHIM Responsive Header

Author: Moses Nyambalo Phiri

  • BIOSAFETY & BIOSECURITY TWG IN LILONGWE TO FINALISE NATIONAL GUIDELINES.

    BIOSAFETY & BIOSECURITY TWG IN LILONGWE TO FINALISE NATIONAL GUIDELINES.

    The first technical working group (TWG) for biosafety and biosecurity took place in Lilongwe on Nov 7 th and 8 th 2023. The purpose of the meeting was to finalise the national guidelines as well as to initiate a long-standing collaboration to safeguard workers and society from dangers of bio-hazards.

    As he opened the meeting, Mr Joseph Bitilinyu, the acting director of PHIM, commented that biosafety and biosecurity has a high priority, both for Malawi and for the African Union.

    The new TWG consist of prominent representatives from several sectors of society. Experts from both animal, human, agriculture and environmental health as well as from police, defence and academia were present. Experts from collaborating partners were also attending the TWG meeting.

    The ongoing outbreak of anthrax in neighbouring Zambia illustrates core questions of biosafety and biosecurity, as it is dangerous for animals and humans and can be used for bioterror. “Biosafety” elates to assuring that biological materials do not harm the persons handling them. “Biosecurity” relates to minimizing the risk that biological material comes astray to threaten the society. Risk assessment is the foundation of good biosafety and biosecurity and should answer three questions; What are the chances of the adverse advent? How severe would it be if it happened? What can we do to mitigate the risks?

    Through two full days, the current situation in Malawi and the rest of the world was presented, but emphasis was put on thorough discussion of each paragraph of the guidelines. It was agreed that Mr.Mabvuto Chiwaula and his team, who has lead this work so far, was trusted to incorporate all the comments into the draft guidelines before getting the final go-ahead.

    On closing the meeting, all members expressed their will to continue their contribution to the TWG. Several participants commented that both the meeting and the document is a milestone of its own, while other added that it is rare to come to such a truly multisectoral meeting. Another commented that “One Health is a song that we are all tuned into after this meeting”.

    Visiting experts from the Norwegian Institute of Public Health, PHIMs sister institute, did not go home empty handed. Head of department dr Siri Feruglio, commented that it was indeed very inspiring and impressive, and even touching, to see the constructive and nice way the members of different parts of society collaborate and contribute for the common good.

  • Point Prevalence Survey and Antibiogram Training Exercise

    Point Prevalence Survey and Antibiogram Training Exercise

    Point Prevalence Survey and Antibiogram Training Exercise

    The AMRNCC with funding from the Eastern, Southern and Central Africa (ESCA) recently conducted a training on the implementation of Point Prevalence Surveys (PPS) and the development of Antibiograms. This training involved 5 participants from 7 health facilities each namely; Mangochi District Hospital, Mzimba District Hospital, Malamulo Hospital, Mzuzu Central Hospital, Zomba Central Hospital, Kamuzu Central Hospital and Queen Elizabeth Central Hospital. The 5 participants included a member from the following cadres; infection prevention and control, nursing, laboratory, clinician and pharmacy. Point prevalence surveys and antibiograms are important and recommended to be done often by health facilities because they inform decisions at health facility level on antimicrobial use and antimicrobial effectiveness, respectively.

    This one-week trainer of trainer session was conducted at Chikho Hotel in Mponela from July 10th to 14th, 2023. Some of the topics covered during this session were; introduction to PPS, planning PPS, collecting data using the PPS tool, introduction to WHONET software, introduction to antibiograms, interpretation and use for guideline development and practical sessions for WHONET, PPS and Antibiograms.

    In order to solidify the knowledge gained during this classroom training, a pilot practical session, took place between July 24th to 28th July 2023.

    During this pilot session, the facility AMS teams performed and Point prevalence survey on antibiotic use using specific in-patient files and developed facility-specific antibiograms utilizing routine laboratory surveillance data. The pilot data collection session was supervised by key experts from the AMNRCC to ensure an efficient learning process and collection of data which may inform facility AMS activities. After the data collection exercise was done, the facilities are analyzing the data before disseminating their facility findings.

    Story in Pictures

    The activity being scaled down to facility level

  • Quality of Malaria and Tuberculosis Genomic Sequencing in Malawi.






    Genomic Surveillance Webinar | PHIM Malawi



    Pathogen Genomic Surveillance

    Quality of Malaria and Tuberculosis
    Genomic Sequencing in Malawi

    Analyzing the quality and impact of Next-Generation Sequencing (NGS) for Malaria and Tuberculosis. Strengthening national diagnostic precision through high-fidelity genomic data.

    Date & Time

    Wed, 22 April | 2 PM – 3 PM


    Lead Scientists & Contributors

    Dr. Matthew Kagoli

    Dr. Matthew Kagoli

    Director, PHIM

    Dr. Kagoli provides comprehensive oversight of the strategic integration of genomic surveillance into Malawi’s National Health Security Framework. He focuses on ensuring that genomic data informs real-time public health responses and national policy. His leadership is pivotal in bridging the gap between laboratory research and community-level interventions. He is a strong advocate for evidence-based decision-making in the Malawian healthcare system.

    Dr. Bitilinyu Bango

    Dr. Bitilinyu Bango

    Deputy Director, PHIM

    Dr. Bango leads the technical implementation of advanced sequencing platforms specifically targeted at Malaria drug-resistance monitoring. He is instrumental in establishing TB lineage characterization protocols that meet international standards. His expertise ensures that the laboratory workflows remain efficient and scalable during public health emergencies. He actively collaborates with international partners to bring cutting-edge technology to the PHIM laboratories.

    Dr. Bernard Mvula

    Dr. Bernard Mvula

    Head of Knowledge Management

    Dr. Mvula is a specialist in bioinformatics and data architecture, focusing on the complex translation of raw sequencing reads into actionable insights. He manages the national genomic data repositories, ensuring data integrity and accessibility for research and surveillance. His work is essential for developing automated pipelines that reduce the turnaround time for diagnostic reporting. He also leads training initiatives to build bioinformatics capacity within the Malawian scientific community.

    Flora Dimba

    Flora Dimba

    Deputy Director, E&S Unit

    Ms. Dimba provides expert leadership in epidemiological field linkage, ensuring that genomic findings for TB and Malaria are geographically mapped. Her work allows for targeted interventions in hotspots where drug resistance or specific lineages are emerging. She coordinates with district health offices to synchronize sample collection with surveillance data. Her efforts are vital for maintaining the resilience and transparency of Malawi’s integrated health monitoring systems.

    Technical Delivery

    Deep dive into laboratory protocols, bioinformatic pipelines, and quality assurance for pathogen sequencing.

    • Sequencing Library Prep Standards
    • Bioinformatics Pipeline Review
    • QA/QC for Clinical Data

    Seminar Program

    Wednesday, 22nd April

    02:00 PM

    Opening & Policy Context

    State of Genomics in Malawi: Dr. Matthew Kagoli

    02:15 PM

    Malaria & TB Quality Assessment

    Benchmarking Sequencing Accuracy: Dr. Bitilinyu Bango

    02:35 PM

    Bio-Surveillance & Resistance Mapping

    Data Integration: Dr. Bernard Mvula & Flora Dimba

    02:50 PM

    Interactive Q&A Session

    Open Floor: Addressing Laboratory Challenges

    Webinar Registration

    Join the specialized session on Pathogen Genomic Quality.

    Research & Resources

    Authored & Published By

    Moses Nyambalo Phiri

    Public Health Institute of Malawi

    Ministry of Health, Republic of Malawi

    Advancing Diagnostic Excellence in Malawi